A Universal Predictive Model for Dose Fall-off in Multileaf Collimator–based Stereotactic Brain Radiosurgery
نویسندگان
چکیده
منابع مشابه
Dose selection in stereotactic radiosurgery.
Selecting optimal doses for radiosurgery requires a thorough consideration of existing dose-response data for radiation injury of brain and surrounding structures and of the doseresponse for the desired endpoint (tumor control, obliteration of a vascular malformation, relief of trigeminal neuralgia, etc.). This paper reviews the radiobiological and physics principles that should be considered i...
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Worldwide, approximately 100,000 patients have undergone stereotactic radiosurgery for a variety of intracranial lesions, of which brain metastases represent the most common treatment indication. This article summarizes the major issues surrounding the management of brain metastases, and also analyzes 21 independent reports of Gamma Knife- or linear accelerator-based radiosurgery, representing ...
متن کاملStereotactic Radiosurgery for Brain Tumors
Stereotactic Radiosurgery (SRS) is a non-invasive technique for the delivery of highly focused ionizing radiation with extreme precision. It is used in neurosurgical practice as a less invasive means of targeting benign and malignant brain tumors, vascular malformations, and functional disorders. Its ability to elicit a desired response (e.g. tumor cell death) with minimal effect on normal surr...
متن کاملDynamic conformal arc cranial stereotactic radiosurgery: implications of multileaf collimator margin on dose-volume metrics.
OBJECTIVE The effect of multileaf collimator (MLC) margin on target and normal tissue dose-volume metrics for intracranial stereotactic radiosurgery (SRS) was assessed. METHODS 118 intracranial lesions of 83 SRS patients formed the basis of this study. For each planning target volume (PTV), five separate treatment plans were generated with MLC margins of -1, 0, 1, 2 and 3 mm, respectively. Id...
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"Stereotactic" is an exact radiotherapy treatment modality which implements invasive and non-invasive facilities for improving precise dose delivery. Stereotactic refers to three-dimensional localization of a specific point in space by a unique set of coordinates that relate to a fixed external reference frame. An accurate delivery of radiation is attainable using these techniques with high pre...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2016
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2016.06.2165